Since hCG administration facilitates ovulation, it has since long been used as part of fertilization programs. Also, other indication is the lack of descent of testicles in boys, a condition called cryptorchidism.

hCG is one of the few drugs of natural origin that, fortunately, still remain in the current Pharmacopoeia. For unknown reasons, most of the research performed on its therapeutic potential deals with investigations related to testicles or ovaries, with comparatively few investigations performed in other clinical fields.

Thousands of articles have been published about the effect of hCG on gonads (testicles or ovaries), but comparatively a small number of these have investigated its vast therapeutic potential on diseases ranging from Kaposi sarcoma,asthma, artheriopaties, thalassemia, osteopenia, glaucoma, cancer.